Interrelationships Between Cardiac Effects of Ouabain, Hypocalcemia and Hyperkalemia
ثبت نشده
چکیده
In dogs anesthetized with pentobarbital, ventricular arrhythmias induced by ouabain were consistently reverted to sinus rhythm by acute lowering of the serum calcium. In ouabain-intoxicated clogs, the depressed and shortened S-T segment was elevated and lengthened by induced hypocalcemia. Potassium administered concomitantly with ouabain exerted a protective effect against ouabain intoxication. Lowering of the serum calcium in animals showing moderately advanced potassium effects in their ECG precipitated acute, fatal potassium poisoning. Ouabain was capable of reversing the tachycardia and pulsus alternans due to hypocalcemia in the face of persistent hypocalcemic tetany.
منابع مشابه
Interrelationships Between Cardiac Effects of Ouabain, Hypocalcemia and Hyperkalemia
In dogs anesthetized with pentobarbital, ventricular arrhythmias induced by ouabain were consistently reverted to sinus rhythm by acute lowering of the serum calcium. In ouabain-intoxicated clogs, the depressed and shortened S-T segment was elevated and lengthened by induced hypocalcemia. Potassium administered concomitantly with ouabain exerted a protective effect against ouabain intoxication....
متن کاملInterrelationships between cardiac effects of ouabain, hypocalcemia and hyperkalemia.
In dogs anesthetized with pentobarbital, ventricular arrhythmias induced by ouabain were consistently reverted to sinus rhythm by acute lowering of the serum calcium. In ouabain-intoxicated clogs, the depressed and shortened S-T segment was elevated and lengthened by induced hypocalcemia. Potassium administered concomitantly with ouabain exerted a protective effect against ouabain intoxication....
متن کاملتغییرات الکتروکاردیوگرافیک ناشی از هیپرکالمی در بیماران مبتلا به نارسایی حاد و نارسایی مزمن کلیه تحت همودیالیز مزمن
Introduction : Hyperkalemia is a common disorder among renal failure patients and is considered as an important internal medicine emergency. On the other hand, considering the non-specific symptoms of hyperkalemia and its similarity to the underlying diseases’ symptoms, the occurrence of dangerous side effects is probable. One of the most important effects is on myocardium. Considering the im...
متن کاملHypocalcemia and hyperkalemia during magnesium infusion therapy in a pre-eclamptic patient
We present a case of prominent hypocalcemia and hyperkalemia attributed to magnesium infusion in a preeclamptic patient. Iatrogenic hypermagnesemia is an underrecognized cause of hypocalcemia and hyperkalemia. Our report illustrates the effects of magnesium therapy on serum calcium and potassium, necessitating close electrolytes monitoring when used.
متن کاملModes of induced cardiac arrest: hyperkalemia and hypocalcemia - Literature review
The entry of sodium and calcium play a key effect on myocyte subjected to cardiac arrest by hyperkalemia. They cause cell swelling, acidosis, consumption of adenosine triphosphate and trigger programmed cell death. Cardiac arrest caused by hypocalcemia maintains intracellular adenosine triphosphate levels, improves diastolic performance and reduces oxygen consumption, which can be translated in...
متن کامل